IGF-1 RECEPTOR BLOCKADE AND STAT1 ACTIVATION SCIENTIFIC SECTION: IMMUNOBIOLOGY In the absence of IGF-1 signaling, IFN-γ suppresses human malignant T cell growth
نویسندگان
چکیده
L.C. performed most experiments of the research, analyzed the data and wrote the manuscript; G.R. performed biochemistry experiments, participated in analyzing the data; A.L. assisted all molecular, biochemistry and cell-biology studies; P.B. performed cell sorting to obtain cell lines stably expressing high levels of mutant IGF-1 receptor; R.C. prepared retroviral vectors and assisted generation and characterization of the transduced cell lines; M.G. performed and analyzed the in vivo experiments; F.N. designed all aspects of the research, coordinated all experimental approaches, recorded and analyzed data, and wrote the manuscript.
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